tirzepatide peptide side effects Effects: What to Expect & How to Manage (2026 Guide) can tirzepatide cause mood swings

Half of the participants took a daily semaglutide tablet while the other half received placebo

Constipation Slower digestion often means slower bowel movements

These findings hint at potential direct effects on the brain , beyond the psychological benefits of weight loss

Tirzepatide is a dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that is the active ingredient in other FDA-approved drugs for the treatment of type 2 diabetes mellitus

Oral GLP-1 drops EllieMD also offers sublingual (under the tongue) drops for both semaglutide and tirzepatide formulations